The MK‑7264‑042 study is enrolling women who leak urine when they cough. This condition is known as chronic cough induced stress urinary incontinence, or cSUI. The MK‑7264‑042 clinical research study is evaluating an investigational drug to see if it may be a safe and effective treatment for cSUI.
Answer a few questions to see if you may qualify for the MK‑7264‑042 study.
Stress urinary incontinence (SUI) means you leak urine unintentionally as a result of pressure, or stress, on your bladder. This stress happens during physical movements or activities, such as coughing, sneezing, running, laughing, or lifting. If you have a persistent cough and leak urine when you cough, you may have cSUI. However, you may not leak every time you cough to have cSUI.
The following factors may put you at increased risk:
Your doctor or a specialist may ask you questions, such as how bad your cough is, how often you cough and how often you leak urine when you cough. A pelvic examination may help determine if there could be any underlying conditions causing the leaking. Other tests or activities that could be important in diagnosing cSUI include:
Therapies and treatments are available to help address urinary leaking. Your doctor may recommend behavioral changes, such as adjusting how much you drink and when you drink or quitting smoking. Other potential therapies include the use of external devices designed to control leaking or surgical options.
About 380 women are expected to participate. You may qualify to participate if you are a woman and:
There may be reasons why you cannot be in this study. The study doctor or staff will discuss this with you.
Before joining the MK‑7264‑042 study, you will be screened to find out if you are eligible. If you are eligible and choose to enroll, your participation will last approximately 22 weeks. It will include 6 scheduled visits to the study clinic and 2 phone calls with the study doctor or staff.
Clinical studies rely on the cooperation of volunteer participants. While you are taking part in this study, you will need to:
The first step involves answering a few questions in an online prescreening questionnaire to see if you are a potential candidate for the study. Depending on your answers, you may be referred to a study clinic for screening.Answer Questions